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Public Health
Expert opinion

2,6-Dihydroxyethylaminotoluene (A138)

Final Opinion


Publication date
25 June 2015
Scientific Committee on Consumer Safety (SCCS)


WG on Hair dyes
SCCS members:Q. Chaudhry, P.J. Coenraads, M. Dusinska, W. Lilienblum, E. Nielsen, T. Platzek, S. C. Rastogi, Ch. Rousselle, J. van Benthem
External experts: A. Bernard, L. Bodin, J. Duus-Johansen, J. Ezendam, A. Giménez-Arnau, E. Mirkova, E. Panteri, T. Vanhaecke
Contact: SANCO-C2-SCCSatec [dot] europa [dot] eu (SANCO-C2-SCCS[at]ec[dot]europa[dot]eu)
On request from: European Commission
SCCS Number: SCCS/1563/15
Adopted on: 25 June 2015

Conclusion of the opinion:

1. In light of the new data provided, does the SCCS consider 2,6-Dihydroxyethylaminotoluene (A138) safe when used as a direct dye and as an ingredient in oxidative hair dye formulations up to a final on-head concentration of 1%?

In the light of the new data provided, SCCS considers that the use of 2,6- dihydroxyethylaminotoluene as an ingredient in oxidative hair dye formulations at a maximum concentration of 1.0% on the head is safe.

2. Does the SCCS have any further scientific concerns with regard to the use of 2,6-Dihydroxyethylaminotoluene (A138) in cosmetic products?

2,6-Dihydroxyethylaminotoluene is a secondary amine, and thus, it is prone to nitrosation. It should not be used together with nitrosating agents. Nitrosamine content should be <50 ppb="" p="">


SCCS, scientific opinion, hair dye, 2,6-dihydroxyethylaminotoluene, A138, directive 76/768/ECC, CAS 149330-25-6

Opinion to be cited as:

SCCS (Scientific Committee on Consumer Safety), Opinion on 2,6-dihydroxyethylaminotoluene, 25 June 2015, SCCS/1563/15.