deoxyarbutin Tetrahydropyranyloxy Phenol

SCCS members: U. Bernauer, Q. Chaudhry, P. Coenraads, G. Degen, M. Dusinska, W. Lilienblum, E. Nielsen, T. Platzek, S. C. Rastogi, Ch. Rousselle, Ja. van Benthem
Former SCCS member: A. Luch
External experts: A. Bernard, J. Duus-Johansen, J. Ezendam, A. Giménez-Arnau, E. Mirkova,E. Panteri, T. Vanhaecke
Contact:SANTE-C2-SCCSec [dot] europa [dot] eu (SANTE-C2-SCCS[at]ec[dot]europa[dot]eu)
On request from: European Commission
SCCS Number: SCCS/1554/15
Adopted on: 25 June 2015

Conclusion of the opinion:

1. Does the SCCS consider, on the basis of the provided scientific data, the use of deoxyarbutin to be safe for consumers in cosmetic products in a concentration up to 3% in face creams?

Although on the basis of the provided scientific data the use of deoxyarbutin as such can be considered safe for consumers in cosmetic products in a concentration up to 3% in face creams, hydroquinone will be formed at levels which raise concerns with regard to the safety of such products during life-cycle of the product (e.g. storage conditions and stability under in-use conditions). Therefore, the overall conclusion of the SCCS is that the use of deoxyarbutin up to 3% in face creams is not safe.

2. And/or does the SCCS have any scientific concerns with regard to the use of deoxyarbutin or related substances known to release hydroquinone in cosmetic products?

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Keywords:

SCCS, scientific opinion, deoxyarbutin, Tetrahydropyranyloxy Phenol, Regulation 1223/2009, CAS 53936-56-4

Opinion to be cited as:

SCCS (Scientific Committee on Consumer Safety), Opinion on desoxyarbutin - Tetrahydropyranyloxy Phenol, 25 June 2015, SCCS/1554/15.