Ethylzingerone - ‘Hydroxyethoxyphenyl Butanone’ (HEPB) - Cosmetics Europe No P98 – CAS No 569646-79-3 Submission II (eye irritation)

WG on Cosmetic Ingredients
SCCS members: U. Bernauer, L. Bodin, Q. Chaudhry, P.J. Coenraads (Chairperson), M. Dusinska, J. Ezendam, E. Gaffet, C. L. Galli, B. Granum, E. Panteri, V. Rogiers, Ch. Rousselle, M. Stepnik, T. Vanhaecke (Rapporteur), S. Wijnhoven
SCCS external experts: A. Simonnard, A. Koutsodimou, W. Uter
Contact: SANTE-C2-SCCSec [dot] europa [dot] eu (SANTE-C2-SCCS[at]ec[dot]europa[dot]eu)
On request from: European Commission
SCCS Number: SCCS/1604/18
Adopted on: 5 March 2019

Conclusion of the opinion:

1. In light of the new studies provided, does the SCCS consider the use of Hydroxyethoxyphenyl Butanone (HEPB) safe with regard to eye irritation, when used as preservative in rinse-off, oral care and leave-on cosmetic products with a maximum concentration of 0.7%?

Based on the new information provided by the Applicant, the SCCS considers the use of Hydroxyethoxyphenyl Butanone (HEPB) as a cosmetic preservative in rinse-off, oral care and leave-on cosmetic products with a maximum concentration of 0.7 % safe with regard to eye irritation.

Keywords:

SCCS, scientific opinion, Ethylzingerone - ‘Hydroxyethoxyphenyl Butanone’(HEPB) - Cosmetics Europe No P98, CAS 569646-79-3, Regulation 1223/2009, SCCS/1604/18