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SCCS Opinion on the inhalation toxicity of the fragrance ingredient Acetylated Vetiver Oil – AVO (CAS No 84082-84-8, EC No 282-031-1) in sprayable cosmetic products - Submission IV

Preliminary Opinion open for comments - deadline for comments: 3 May 2024

Details

Publication date
5 March 2024
Author
Scientific Committee on Consumer Safety (SCCS)

Description

SCCS members: U. Bernauer, L. Bodin, Q. Chaudhry, P.J. Coenraads (Chairperson), J. Ezendam, E. Gaffet, C. L. Galli (Rapporteur), E. Panteri, V. Rogiers, Ch. Rousselle, M. Stepnik, T. Vanhaecke, S. Wijnhoven
SCCS external experts: E. Benfentati, N. Cabaton, E. Corsini, A. Koutsodimou, H. Louro, W. Uter, N. von Goetz
Contact: SANTE-SCCSatec [dot] europa [dot] eu (SANTE-SCCS[at]ec[dot]europa[dot]eu)
On request from: European Commission
SCCS Number: SCCS/1663/24
Adopted on: 28 February 2024

Conclusion of the opinion:

(1) In light of the data provided concerning inhalation toxicity, does the SCCS consider Acetylated Vetiver Oil (AVO) safe when used in sprayable cosmetic products with intended maximum concentrations (IMCs) of 0.9% (w/w) in fragrance pump sprays, 0.05% (w/w) in deodorant sprays and 0.1% (w/w) in hairsprays and body lotion sprays?

Having considered the data provided concerning inhalation toxicity and aggregate exposure, the SCCS considers Acetylated Vetiver Oil (AVO) (with 1% alpha-tocopherol) safe when used at the intended maximum concentrations (IMCs) of 0.9% (w/w) in fragrance pump sprays, 0.05% (w/w) in deodorant sprays and 0.1% (w/w) in hairsprays and body lotion sprays. The findings of an in vitro study using Mucilair™ also support this conclusion.

(2) Does the SCCS have any further scientific concerns regarding the use of Acetylated Vetiver Oil (AVO) in cosmetic products?

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Keywords:

SCCS, scientific opinion, Acetylated Vetiver Oil (AVO), Regulation 1223/2009, Acetylated Vetiver oil – AVO, CAS No 84082-84-8, EC No 282-031-1, SCCS/1663/24

Opinion to be cited as:

SCCS (Scientific Committee on Consumer Safety), Opinion on the inhalation toxicity of the fragrance ingredient Acetylated Vetiver Oil – AVO (CAS No 84082-84-8, EC No 282-031-1) in sprayable cosmetic products - Submission IV, SCCS/1663/24, preliminary version of 28 February 2024.

Files

5 MARCH 2024
sccs_o_285.pdf